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CHEM101 Introductory University Chemistry I Course Page

Description: Atoms and molecules, states of matter, chemistry of the elements. Prerequisite: Chemistry 30, or equivalent.

CHEM102 Introductory University Chemistry II Course Page

Description: Rates of reactions, thermodynamics and equilibrium, electro-chemistry, modern applications of chemistry. Prerequisite: CHEM 101.

CHEM103 Introductory University Chemistry I Course Page

Description: Atoms and molecules, states of matter, chemistry of the elements. Prerequisite: Chemistry 30, or equivalent. Note: Restricted to Engineering students only. Other students who take this course will receive *3.0.

CHEM105 Introductory University Chemistry II Course Page

Description: Rates of reactions, thermodynamics and equilibrium, electrochemistry, modern applications of chemistry. Prerequisite: CHEM 103. Note: Restricted to Engineering students only. Other students who take this course will receive *3.0.

CHEM164 Organic Chemistry I Course Page

Description: The study of basic molecular structure and reactivity of organic compounds based on their functional groups. Introduction to nomenclature, three dimensional structure, physical properties, and reactivity of compounds of carbon. Functional groups covered will emphasize alkanes, alkenes, alkynes, alkyl halides, alcohols, and some aromatics. Examples will include hydrocarbons (petroleum products), halogenated organic compounds (e.g., pesticides), and polymers of industrial importance which may be found in everyday life. Note: Students who already have credit in CHEM 101 must register in CHEM 261. Prerequisite: Chemistry 30 or equivalent. Restricted to students with CHEM 30 averages of 90% or higher, or departmental approval.

CHEM211 Quantitative Analysis I Course Page

Description: Principles, methods, and experimental applications emphasizing solution phase equilibria, titrimetry, volumetric laboratory skills, evaluation of experimental data, and experimental applications of electrochemistry. Includes examples of organic and inorganic analysis. Prerequisite: CHEM 102 or SCI 100.

CHEM213 Quantitative Analysis II Course Page

Description: A continuation of CHEM 211 emphasizing the principles, methods, and experimental applications of separation techniques, and atomic and molecular spectrometry, and evaluation of experimental data. Includes examples of organic and inorganic analysis and use of the analytical literature. Prerequisite: CHEM 211. Students who have previously taken CHEM 313 may not take CHEM 213 for credit.

CHEM241 Introduction to Inorganic Chemistry Course Page

Description: The chemistry of main-group elements including a survey of the structure, bonding, and reactivity of their compounds. Transition-metal chemistry will be introduced. The course will include applications in industrial, biochemical, environmental, and materials science. Students who have obtained credit for CHEM 331 cannot take CHEM 241 for credit. Prerequisites: CHEM 102 or 105 and CHEM 161 or 164 or 261; or SCI 100.

CHEM243 Advanced Inorganic Chemistry Course Page

Description: An extension of CHEM 241 with emphasis on the bonding, structure, and reactivity of transition-metal elements. The course will include applications in industrial, biochemical, environmental, and materials science. For Chemistry Honors and Specialization students only, except by consent of Department. Note: This course may not be taken for credit if credit has already been received in CHEM 341. Prerequisites: CHEM 241 or consent of Department.

CHEM261 Organic Chemistry I Course Page

Description: The correlation of structure and chemical bonding in carbon compounds with the physical properties and chemical reactivity of organic molecules. Discussion will be based on functional groups with emphasis on hydrocarbons and derivatives that contain halogens, oxygen, sulfur, and the hydroxy group. Introduction to stereochemistry, three dimensional structure, reaction mechanisms, especially addition to double bonds, nucleophilic substitution and elimination reactions. Prerequisite CHEM 101 or 103. Note: Students who have obtained credit for CHEM 161 or 164 cannot take CHEM 261 for credit. Engineering students who take this course will receive *4.5.

CHEM263 Organic Chemistry II Course Page

Description: Continuation of the structural and chemical properties of the basic functional groups of organic compounds including alkynes, aromatic compounds, aldehydes, ketones, carboxylic acids and their derivatives and amines. Illustration of these functional groups in natural products such as carbohydrates, amino acids and proteins, nucleic acids and lipids. Discussion of the application of spectroscopic methods for the structure determination in simple organic molecules. Prerequisites: CHEM 161 or 164 or 261 or SCI 100. Note: Students who have obtained credit for CHEM 163 cannot take CHEM 263 for credit.

CHEM282 Atomic and Molecular Structure Course Page

Description: An introduction to the quantum view of nature with applications to atomic and molecular structure. Methods to describe the quantum world are introduced, used to describe simple electronic, vibrational and rotational structure of model systems, and applied to the hydrogen atom, many-electron atoms, simple diatomic molecules, and the electronic structure of polyatomic molecules. The laboratory portion of the course consists of practical applications enriching and illustrating the lecture material, and incorporates the use of computers as a routine aid to processing experimental results. Prerequisites: CHEM 102 or 105; one 200-level CHEM course; MATH 115 and PHYS 124 or 144. Corequisite: PHYS 146 if PHYS 144 presented as a prerequisite instead of PHYS 124. Students with SCI 100 have prerequisite requirements.

CHEM298 Introductory Spectroscopy Course Page

Description: The course is an integrated introduction to the qualitative and instrumentation aspects of spectroscopy and its applications in chemistry. The subjects will include: absorption, emission, vibrational and rotational spectroscopy of atoms and molecules; and nuclear magnetic resonance spectroscopy. For Chemistry Honors and Specialization students only, except by consent of Department. Prerequisite: CHEM 102 or 105 or SCI 100; CHEM 163 or 263.

CHEM299 Research Opportunity Program in Chemistry Course Page

Description: A credit/no-credit course for supervised participation in a faculty research project. Normally taken after completion of a minimum of *30 but not more than *60 in a program in the Faculty of Science. Prerequisite: GPA of 2.5 or higher, CHEM 101 or 161 or SCI 100; and consent of Department. Specific projects may require additional prerequisites. Project and course information available at ROP website or Department of Chemistry. Prospective enrollees in CHEM 299 must apply to Department of Chemistry. Application does not guarantee an ROP position. Credit for this course may be obtained twice.

CHEM300 Introduction to Industrial Chemistry Course Page

Description: A credit/no-credit course that introduces students to the practices, environment, concepts, and other issues associated with the industrial workplace. Course includes lectures by professionals from the local chemical industry, industrial tours, and professional skills development such as resume writing and interviewing. Normally taken after completion of a minimum of 60 but not more than 90 units of course weight in a program in the Department of Chemistry. The course is offered for Chemistry Honors and Specialization students, and for General Science students with consent. Prerequisite: GPA of 2.3 or higher and consent of Department.

CHEM303 Environmental Chemistry I Course Page

Description: The chemistry of environmental processes. Atmospheric chemistry; thermal and photochemical reactions of atmospheric gases including oxygen, ozone, hydroxy radical, and oxides of nitrogen and sulfur. Aquatic chemistry; characterization, reactions, and equilibria of dissolved species, water purification treatments. Metals and organohalides in the environment. Risk assessment. Prerequisites: CHEM 102 or SCI 100; CHEM 164 or 261; CHEM 263; and one 200-level CHEM course or CH E 243.

CHEM305 Environmental Chemistry II Course Page

Description: The lecture and laboratory portions of this course will highlight adsorption from aqueous solutions, convective/diffusive transport, vapour/solution equilibria, coagulation of colloids, sedimentation, ion exchange, computer modeling of complex systems, trace analysis of pesticides, chemical treatment of hazardous wastes. Quantitative calculations will be emphasized. The lecture component will provide theoretical background for experiments and instrumentation used for chemical measurements. Prerequisites: CHEM 263; CHEM 213 or 298 or 313; CHEM 303 or 373. Note: Restricted to students in the Environmental Physical Sciences and Chemistry (Honors, Specialization, and General Science with concentration in Chemistry) programs.

CHEM313 Instrumentation in Chemical Analysis Course Page

Description: Instrumentation and analytical applications of spectroscopic, chromatographic and electroanalytical methods are discussed and applied in the laboratory. Prerequisites: CHEM 211; *6 in junior Physics recommended.

CHEM333 Inorganic Materials Chemistry Course Page

Description: Fundamentals of the synthesis, structure and properties of inorganic solids, thin films, and nanoscale materials, to be complemented with case studies of modern applications of inorganic materials; selected topics such as catalysis, molecular and nanoparticle-based computing, telecommunications, alternative energies, superconductivity, biomedical technologies, and information storage will be discussed. Techniques for characterization and analysis of materials on the nano and atomic level will be introduced. Prerequisite: CHEM 241.

CHEM361 Organic Chemistry Course Page

Description: Mechanisms and reactions of aromatic and aliphatic compounds. Prerequisites: CHEM 102 or SCI 100; CHEM 163 or 263.

CHEM363 Organic Chemistry Course Page

Description: A continuation of CHEM 361. Prerequisite: CHEM 361.

CHEM371 Energetics of Chemical Reactions Course Page

Description: A study of the implications of the laws of thermodynamics for transformations of matter including phase changes, chemical reactions, and biological processes. Topics include: thermochemistry; entropy change and spontaneity of processes; activity and chemical potential; chemical and phase equilibria; properties of solutions; simple one- and two-component phase diagrams. The conceptual development of thermodynamic principles from both macroscopic and molecular levels, and the application of these principles to systems of interest to chemists, biochemists, and engineers will be emphasized. Note: This course may not be taken for credit if credit has already been received in CHEM 271. Prerequisites: CHEM 102 or 105; MATH 101 or 115. SCI 100 may be used in lieu of CHEM 102 and MATH 115. Engineering students who take this course will receive *4.5.

CHEM373 Physical Properties and Dynamics of Chemical Systems Course Page

Description: A continuation of CHEM 371 in which the physical properties of chemical systems and the dynamics and energetics of chemical processes are discussed. Topics include: colligative properties; electrochemical cells and ion activities, implications for ionic equilibria; kinetic theory and transport properties of gases and liquids; surfaces and colloid chemistry; reaction dynamics, detailed mechanisms of chemical reactions, catalysis. The emphasis will be on the development of principles of physical chemistry and their application to properties and processes of interest to chemists, biochemists, and engineers. Note: This course may not be taken for credit if credit has already been received in CHEM 273 or 275. Prerequisite: CHEM 371 or 271.

CHEM398 Molecular Spectroscopy Course Page

Description: An integrated course in the quantitative and more advanced aspects of spectroscopy and its applications in chemistry. The subjects may include: absorption, emission, dichroism, vibrational and rotational spectroscopy of molecules; time-resolved spectroscopy; nuclear magnetic resonance spectroscopy; surface-specific spectroscopies. Prerequisites: CHEM 282; 298.

CHEM399 Research Experience in Chemistry Course Page

Description: A credit/no-credit course for participation in a research project under the direction of a member of the Department. Students taking CHEM 401 or 403 cannot concurrently take CHEM 399. Credits for CHEM 399 count as science options in all chemistry programs. Credit for this course may be obtained up to four times. Prerequisites: Departmental permission. *9 of 200-level chemistry or *3 of 300-level chemistry.

CHEM400 Science Internship Practicum Course Page

Description: Required by all students who have just completed the on-site portion of the Science Internship Program. Must be completed during the first academic term following return to full-time studies. Note: A grade of F to A+ will be determined by the student's job performance as evaluated by the employer, by the student's performance in the completion of an internship practicum report, and by the student's ability demonstrated in an oral presentation. This course cannot be used in place of a senior-level CHEM option. Prerequisites: WKEXP 955 and 956.

CHEM401 Introduction to Chemical Research Course Page

Description: Introduction to methods of chemical research. Investigational work under the direction of a member of the Department. The results of the research will be submitted to the Department as a report which will be graded. The student must also make an oral presentation of this work to the Department. For students in the fourth year of Honors or Specialization Chemistry. Students should consult with the Course Coordinator four months prior to starting the course. Prerequisites: a 300-level CHEM course and consent of the Course Coordinator.

CHEM403 Chemical Research Course Page

Description: Investigational work under the direction of a member of the Department. The results of the research will be submitted to the Department as a report, which will be graded. The student must also make an oral presentation of this work to the Department. Prerequisite or corequisite: CHEM 401.

CHEM405 Special Topics in Chemistry Course Page

Description: Prerequisite: a 300- level CHEM course and consent of Instructor. Course may be repeated for credit, provided there is no duplication of specific topic.

CHEM406 Special Topics in Chemistry Course Page

Description: Prerequisites: vary depending on topic. Check course notes on Bear Tracks for specific prerequisites.

CHEM419 Bioanalytical and Environmental Analytical Chemistry Course Page

Description: This is a two-part course with the first half consisting of an introduction to bioanalytical chemistry and the second half consisting of environmental analytical chemistry. The bioanalytical component will focus on methods used to analyze biomolecules and the analytical methods that exploit the molecular recognition properties of biomolecules. Topics may include antibodies, immunoassays, surface plasmon resonance, biosensors, gel electrophoresis, DNA sequencing, microscopy and imaging. The environmental component will cover methods and strategies used to measure trace levels of contaminants in complex environmental matrices, including air, water, soil, and biota. Topics may include sample handling and quality control, sample preparation and matrix effects, modern analytical instrumentation, measurement of reactive species, and online analysis techniques. Prerequisites: BIOCH 200 and CHEM 313 or BIOCH 200, CHEM 213 and a 300-level Chemistry course.

CHEM424 Optical Spectroscopy and Electrochemistry Course Page

Description: Optical spectroscopy and electrochemistry and principles and applications to chemical analysis. Electronic and vibrational spectroscopy for probing and monitoring chemical and biochemical systems. Electrode kinetics, mass transport, and voltammetry for electroanalysis. Prerequisite: CHEM 313.

CHEM425 Separations and Mass Spectrometry Course Page

Description: Concepts and techniques in chromatography, mass spectrometry, and chromatography/MS combinations. Examples of modern instrumentation as well as applications to chemical, biochemical, and biomedical analysis. Prerequisite: CHEM 313.

CHEM434 X-ray Crystallography Course Page

Description: An introduction to structure determination by single-crystal X-ray diffraction methods. Topics include X-ray diffraction, crystal symmetry, experimental methods, structure solution, refinement, crystallographic software, and interpretation of crystal structure data. Prerequisite: CHEM 243 and one 300-level CHEM course; or CHEM 333 or 341; or consent of the instructor.

CHEM436 Synthesis and Applications of Inorganic and Nano-materials Course Page

Description: Introduction to methods of synthesizing inorganic materials with control of atomic, meso- and micro-structure. Topics include sol-gel chemistry, chemical vapor deposition, solid state reactions, solid-state metathesis and high-temperature self-propagating reactions, template directed syntheses of micro and mesoporous materials, micelles and colloids, synthesis of nanoparticles and nanomaterials. Applications of these synthetic techniques to applications such as photonic materials, heterogeneous catalysts, magnetic data storage media, nanoelectronics, display technologies, alternative energy technologies, and composite materials will be discussed. Prerequisite: CHEM 243 and one 300-level CHEM course; or CHEM 341; or CHEM 333; or consent of the instructor.

CHEM437 Transition Metal Chemistry Course Page

Description: CHEM 437 is an introduction to organotransition metal chemistry. The course will deal with the synthesis, basic bonding, and reactivity of organotransition metal complexes. Topics to be covered include transition metal complexes of hydrides, phosphines, carbonyls, olefins, alkynes, polyolefins, cyclopentadienyl and related cyclic pi-ligands; metal-carbon sigma- and multiple bonds. The application of these complexes to homogeneous catalysis and to organic synthesis will be discussed when appropriate. Prerequisite: CHEM 243 and one 300-level CHEM course; or CHEM 341; or consent of the instructor.

CHEM438 Solid State Chemistry Course Page

Description: Introduction to the chemistry of extended inorganic solids. The topics covered include synthesis, symmetry, descriptive crystal chemistry, bonding, electronic band structures, characterization techniques, and phase diagrams. The correlation of structure with properties of electronic and magnetic materials will be discussed. Prerequisite: CHEM 243 and one 300-level CHEM course; or CHEM 333 or 341 or consent of the instructor.

CHEM443 Asymmetric Catalysis Course Page

Description: An introductory course on asymmetric catalysis. Emphasis will be on reactions catalyzed by chiral transition metal complexes, but non-metal catalyzed reactions and heterogeneous catalysis will be covered. Topics include the general principles of catalysis; mechanisms of common steps in catalytic cycles; rapid pre-equilibrium and steady-state kinetic treatments of catalytic rates; the origins of catalytic selection; and the strategies and principles of new catalyst, ligand, and reaction development. The course will include a survey of common enantioselective catalytic reactions and daily examples from ASAP articles that illustrate the principles and theories being taught in the course. Introductory level knowledge of transition metal and organic chemistry is required. Prerequisite: CHEM 243 and one 300-level chemistry course.

CHEM444 Characterization Methods in Nanoscience Course Page

Description: Introduction to techniques in determining the composition and structure of materials on the nanometer scale. Characterization of atomic, meso-, and microstructure of materials including impurities and defects. Major topics will include electron microscopy (transmission, scanning, and Auger) and associated spectroscopies (EDX, EELS), surface sensitive spectroscopies (e.g., XPS, AES, IR) and spectrometry (SIMS), synchrotron techniques, X-ray absorption, fluorescence and emission, and scanned probe microscopies (AFM, STM, etc.). The strengths, weaknesses, and complementarity of the techniques used will be examined via case studies on the characterization of real-world nanotechnologies, such as heterogeneous catalysts, surfaces and interfaces in semiconductor devices, organic monolayers on metals and semiconductors, nanotube- and nanowire-based electronics, and biocompatible materials. Prerequisite: 4th year standing or consent of instructor.

CHEM451 Chemical Biology Course Page

Description: Introduction to the methods used to analyze and manipulate biological systems using engineered biomolecules and synthetic organic molecules. Topics may include biomolecule structure and function, enzymology, molecular biology, protein engineering, genome engineering, bioinformatic methods, inhibitor design, library screening methods, fluorescent probes, bioorthogonal chemistry, and various chemical biology methods. Prerequisites: BIOCH 200 and CHEM 361 (can be taken as co-requisite).

CHEM454 Bioconjugate Chemistry Course Page

Description: Discussion of organic reactions to modify or label biopolymers including proteins, carbohydrates, and nucleic acids. Topics will include mechanistic and methodological details of commonly employed reactions used for chemoselective labeling or modification of biomolecules to produce synthetic vaccines, antibody-drug conjugates, and native chemical ligation will be discussed. Prerequisites: CHEM 361 and BIOCH 200, or consent of instructor.

CHEM461 Qualitative Organic Analysis Course Page

Description: Introductory discussion of the physical techniques used in organic chemistry research for the separation/purification and structural elucidation of organic compounds. Emphasis is on the combined use of modern spectrometric techniques for structure determination, with particular focus on an introduction to modern NMR spectroscopy. Prerequisite: CHEM 363 or consent of Instructor.

CHEM462 Physical Organic Chemistry Course Page

Description: Discussion of organic structural theories, intramolecular and intermolecular interactions in organic chemistry, and the mechanisms and reactive intermediates involved in organic reactions. Prerequisite: CHEM 363 or consent of Instructor.

CHEM463 Organic Synthesis Course Page

Description: Discussion of the different concepts of chemoselective, regioselective and stereoselective reactions of organic compounds. Main classes of reactions described are oxidations, reductions, functional group protection, and carbon-carbon bond formation methods for single, double, and triple bonds. Emphasis on modern methodology for organic synthesis, including asymmetric catalysis and transition-metal catalyzed methods such as cross-coupling chemistry. Prerequisite: CHEM 363 or consent of Instructor.

CHEM464 BIOCONJUGATE CHEMISTRY Course Page
No description available for this course.
CHEM477 Molecular Symmetry and Spectroscopy Course Page

Description: Application of the principles of molecular symmetry to molecular properties. Topics include group theory with emphasis on vibrational motion and normal vibrations; quantum mechanics of vibration and rotation; magnetic resonance spectroscopy; perturbation methods; selection rules in rotational, infrared, and Raman spectroscopy; molecular symmetry and molecular orbitals; electronic spectroscopy of polyatomic molecules. Prerequisite: CHEM 383; or CHEM 282 and CHEM 298 and one 300-level Chemistry course; or consent of Instructor.

CHEM479 Molecular Kinetics Course Page

Description: Rate laws for simple and complex reactions, reaction mechanisms, potential energy surfaces, molecular dynamics, theories of reaction rates, catalysis, with application to gas and liquid phase reactions, photochemical reactions in chemistry and biology, and enzyme catalysis. Prerequisites: CHEM 273 or CHEM 373; MATH 215, PHYS 230, and a 300-level Chemistry course.

CHEM493 Computational Chemistry Course Page

Description: The focus is on applications in this course which introduces the student to contemporary computational quantum chemistry (Hartree-Fock, post-Hartree-Fock, and density functional theory methods), using the state of-the-art computer code GAMESS-US running on UNIX workstations and computer servers. Elementary introduction to the UNIX operating system is given. Subjects include: basis sets; optimization of molecular geometry; prediction of molecular properties; calculation of infra-red and Raman spectra; excited electronic states; solvent effects; computational thermochemistry; mechanisms of chemical reactions; visualization of results. Assignments in the course allow the student to acquire practical computational experience that relates to chemistry. Prerequisite: CHEM 383 or CHEM 282 and one 300-level chemistry course or consent of Instructor.

CHEM495 Molecular Dynamics and its Applications Course Page

Description: An introduction to Molecular Dynamics and its applications. The fundamentals of statistical mechanics are reviewed and computational tools such as molecular dynamics and Monte Carlo methods are presented. Applications include the study of structural properties of liquids, the diffusion of a solute in a solvent, the dynamics of proton transfer, and the calculation of rate constants. These topics will be exemplified using computer simulations as problem set assignments. Some lectures will take place in the computer laboratory where visualization tools will be used to illustrate various applications of molecular dynamics. Prerequisite: CHEM 282 and one 300-level CHEM course; or CHEM 383; or consent of the instructor.

CHEM502 Departmental Research Seminar Course Page

Description: Course may be repeated.

CHEM511 Biomolecular Chemistry Course Page

Description: Six week course with topics that may include: biomolecule structure and function, enzymology, molecular biology, protein engineering, bioconjugate chemistry, bioinformatics and molecular visualization. Not open to students with credit in CHEM 419.

CHEM512 Optical Spectroscopy Course Page

Description: Six week course on optical spectroscopy. Topics may include electromagnetic spectrum, transitions and selection rules, instrumentation, atomic spectroscopy, molecular absorption, fluorescence, vibrational spectroscopy, applications of optical spectroscopy. Not open to students with credit in CHEM 424.

CHEM514 Electrochemistry Course Page

Description: Six week course on electrochemistry. Topics may include electrochemical potentials, junction potentials, interfaces, potentiometry/ion selective electrodes, kinetics, electron transport theory, mass transport, voltammetry, microelectrodes, solid electrodes. Not open to students with credit in CHEM 424.

CHEM515 Environmental Analytical Chemistry Course Page

Description: Six week course on the methods and strategies used to measure trace levels of contaminants in complex environmental matrices, including air, water, soil, and biota. Topics may include sample handling and quality control, sample preparation and matrix effects, modern analytical instrumentation, measurement of reactive species, and online analysis techniques. Not open to students with credit in CHEM 419.

CHEM516 Separations Course Page

Description: Six week course on separations with topics that may include LC, GC, intermolecular forces, retention mechanisms, gradient elution, separation optimization, band broadening, HPLC modes-reversed phase, size exclusion, ion exchange, HILIC. Not open to students with credit in CHEM 425.

CHEM518 Mass Spectrometry Course Page

Description: Six week course on mass spectrometry with topics that may include mass analyzers, sample introduction techniques, ionization techniques, ion detection and data systems, applications. Not open to students with credit in CHEM 425.

CHEM519 Bioanalytical Chemistry Course Page

Description: Six week course with topics that may include antibodies, immunoassays, surface plasmon resonance, biosensors, gel electrophoresis, DNA sequencing, microscopy and imaging. Not open to students with credit in CHEM 419.

CHEM534 X-ray Crystallography Course Page

Description: An introduction to structure determination by single-crystal X-ray diffraction methods. Topics include X-ray diffraction, crystal symmetry, experimental methods, structure solution, refinement, crystallographic software, and interpretation of crystal structure data. Not open to students with credit in CHEM 433 or 434.

CHEM536 Synthesis and Applications of Inorganic and Nano-materials Course Page

Description: Introduction to methods of synthesizing inorganic materials with control of atomic, meso-, and micro-structure. Topics include sol-gel chemistry, chemical vapor deposition, solid-state reactions, solid-state metathesis and high-temperature self-propagating reactions, template-directed syntheses of micro and mesoporous materials, micelles and colloids, synthesis of nanoparticles and nanomaterials. Applications of these synthetic techniques to applications such as photonic materials, heterogeneous catalysts, magnetic data storage media, nanoelectronics, display technologies, alternative energy technologies, and composite materials will be discussed. Not open to students with credit in CHEM 436.

CHEM537 Transition Metal Chemistry Course Page

Description: Graduate level course on organotransition metal chemistry. The course will deal with the synthesis, bonding, and reactivity of organotransition metal complexes. Topics to be covered include transition metal complexes of hydrides, phosphines, carbonyls, olefins, alkynes, polyolefins, cyclopentadienyl and related cyclic pi-ligands; metal-carbon sigma- and multiple bonds. The application of these complexes to homogeneous catalysis and to organic syntheses will be discussed when appropriate. Prerequisite: consent of instructor. Not open to students with credit in CHEM 437.

CHEM538 Solid State Chemistry Course Page

Description: Introduction to the chemistry of extended inorganic solids. The topics covered include synthesis, symmetry, descriptive crystal chemistry, bonding, electronic band structures, characterization techniques, and phase diagrams. The correlation of structure with properties of electronic and magnetic materials will be discussed. Not open to students with credit in CHEM 438.

CHEM543 Asymmetric Catalysis Course Page

Description: An introductory course on asymmetric catalysis. Emphasis will be on reactions catalyzed by chiral transition metal complexes, but non-metal catalyzed reactions and heterogeneous catalysis will be covered. Topics include the general principles of catalysis; mechanisms of common steps in catalytic cycles; rapid pre-equilibrium and steady-state kinetic treatments of catalytic rates; the origins of catalytic selection; and the strategies and principles of new catalyst, ligand, and reaction development. The course will include a survey of common enantioselective catalytic reactions and daily examples from ASAP articles that illustrate the principles and theories being taught in the course. Introductory level knowledge of transition metal and organic chemistry is required. Not open to students with credit in CHEM 443 or 533.

CHEM544 Characterization Methods in Nanoscience Course Page

Description: Introduction to techniques in determining the composition and structure of materials on the nanometer scale. Characterization of atomic, meso-, and micro-structure of materials including impurities and defects. Major topics will include electron microscopy (transmission, scanning, and Auger) and associated spectroscopies (EDX, EELS), surface sensitive spectroscopies (e.g., XPS, AES, IR) and spectrometry (SIMS), synchrotron techniques, X-ray absorption, fluorescence and emission, and scanned probe microscopies (AFM, STM, etc.). The techniques will be examined through real-world nanotechnology case studies. Not open to students with credit in CHEM 444.

CHEM545 Special Topics in Inorganic Chemistry Course Page
No description available for this course.
CHEM551 Chemical Biology I Course Page

Description: Six week course that provides an introduction to the structure and function of the major classes of biological macromolecules. Particular emphasis will be placed on approaches for modifying biomolecule structure using chemical biology and molecular biology methods. Not open to students with credit in CHEM 451.

CHEM553 Chemical Biology II Course Page

Description: Six week course that provides an introduction to modern chemical biology methods with particular emphasis on the use of synthetic organic molecules and modified biomacromolecules as tools to probe biological systems. Not open to students with credit in CHEM 451.

CHEM554 Bioconjugate Chemistry Course Page

Description: Graduate-level discussion of organic reactions to modify or label biopolymers including proteins, carbohydrates, and nucleic acids. Topics will include mechanistic and methodological details of commonly employed reactions used for chemoselective labeling or modification of biomolecules to produce synthetic bioconjugates. Applications including synthetic vaccines, antibody-drug conjugates, and native chemical ligation will be discussed. Prerequisite: 1 year of introductory organic chemistry and 1 term of biochemistry, or consent of instructor. Not open to students with credit in CHEM 464.

CHEM561 Qualitative Organic Analysis Course Page

Description: Introductory graduate-level discussion of the physical techniques used in organic chemistry research for the separation/purification and structural elucidation of organic compounds. Emphasis is on the combined use of modern spectrometric techniques for structure determination, with particular focus on an introduction to modern one- and two-dimensional NMR spectroscopy. There is a laboratory component to this course. Not open to students with credit in CHEM 461.

CHEM562 Physical Organic Chemistry Course Page

Description: Graduate-level discussion of organic structural theories, intramolecular and intermolecular interactions in organic chemistry, and the mechanisms and reactive intermediates involved in organic reactions. Not open to students with credit in CHEM 462 or 465.

CHEM563 Organic Synthesis Course Page

Description: Graduate-level discussion of the different concepts of chemoselective, regioselective and stereoselective reactions of organic compounds. Main classes of reactions described are oxidations, reductions, functional group protection, and carbon-carbon bond formation methods for single, double, and triple bonds. Emphasis on modern methodology for organic synthesis, including asymmetric catalysis and transition-metal catalyzed methods such as cross-coupling chemistry. Not open to students with credit in CHEM 463 or 467.

CHEM564 BIOCONJUGATE CHEMISTRY Course Page
No description available for this course.
CHEM577 Molecular Symmetry and Spectroscopy Course Page

Description: Application of the principles of molecular symmetry to molecular properties. Topics include group theory with emphasis on vibrational motion and normal vibrations; quantum mechanics of vibration and rotation; magnetic resonance spectroscopy; perturbation methods; selection rules in rotational, infrared, and Raman spectroscopy; molecular symmetry and molecular orbitals; electronic spectroscopy of polyatomic molecules. Not open to students with credit in CHEM 477.

CHEM579 Molecular Kinetics Course Page

Description: Rate laws: for simple and complex reactions, reaction mechanisms, potential energy surfaces, molecular dynamics, theories of reaction rates, catalysis, with application to gas and liquid phase reactions, photochemical reactions in chemistry and biology, and enzyme catalysis. Not open to students with credit in CHEM 479.

CHEM593 Computational Chemistry Course Page

Description: The focus is on applications in this course which introduces the student to contemporary computational quantum chemistry (Hartree-Fock, post-Hartree-Fock, and density functional theory methods), using the state-of-the-art computer code GAMESS-US running on UNIX workstations and computer servers. Elementary introduction to the UNIX operating system is given. Subjects include: basis sets; optimization of molecular geometry; prediction of molecular properties; calculation of infra-red and Raman spectra; excited electronic states; solvent effects; computational thermochemistry; mechanisms of chemical reactions; visualization of results. Assignments in the course allow the student to acquire practical experience that relates to chemistry. Term projects focus on chemistry related to student's research area. Not open to students with credit in CHEM 493.

CHEM595 Molecular Dynamics and its Applications Course Page

Description: An introduction to Molecular Dynamics and its applications. The fundamentals of statistical mechanics are reviewed and computational tools such as molecular dynamics and Monte Carlo methods are presented. Applications include the study of structural properties of liquids, the diffusion of a solute in a solvent, the dynamics of proton transfer, and the calculation of rate constants. These topics will be exemplified using computer simulations as problem set assignments. Some lectures will take place in the computer laboratory where visualization tools will be used to illustrate various applications of molecular dynamics. Not open to students with credit in CHEM 495.

CHEM612 Advanced Optical Spectroscopy Course Page

Description: Six week course with topics that may include: sources, wavelength analyzers, interferometers, detectors, signal/noise, signal processing, advanced Raman spectroscopy, single molecule fluorescence and fluorescence imaging, Surface Enhanced Raman Spectroscopy. Prerequisite: CHEM 512.

CHEM614 Advanced Electrochemistry Course Page

Description: Six week course with topics that may include: CV and chemical reactions, microelectrode applications, carbon electrodes, modified electrode surfaces, micro-fabricated sensors, scanning probe microscopy, spectroelectrochemistry, rotating disk electrochemistry, AC voltammetry. Prerequisite: CHEM 514.

CHEM616 Advanced Separations Course Page

Description: Six week course with topics that may include: multidimensional separations, ion chromatography, CE, biological HPLC, advanced sample preparation/introduction techniques. Prerequisite: CHEM 516.

CHEM618 Advanced Mass Spectrometry Course Page

Description: Six week course with topics that may include: mass analyzers and ionization techniques, vacuum systems, advanced sample introduction techniques, tandem MS, mass spectral interpretation, quantitative MS, MS applications. Prerequisite: CHEM 518.

CHEM623 Special Topics in Advanced Analytical Chemistry Course Page

Description: Course may be repeated for credit, provided there is no duplication of specific topic.

CHEM667 Special Topics in Synthetic Chemistry Course Page

Description: Advanced treatment of selected topics in modern synthetic organic chemistry, drawn from one or more of the following: (1) advanced methodology for organic synthesis, (2) carbohydrate structure and synthesis, (3) organometallic methodology for organic synthesis, and (4) solid-phase organic synthesis and combinatorial chemistry. Other topics appropriate to the category may also be offered. Course may be repeated for credit, provided there is no duplication of specific topic. Prerequisite: CHEM 563 or consent of Instructor.

CHEM669 Special Topics in Bio-organic Chemistry Course Page

Description: Advanced discussion of selected topics in modern bio-organic chemistry, drawn from one or more of the following: (1) natural products and secondary metabolism, (2) nucleic acid chemistry, and (3) organic and biophysical carbohydrate chemistry. Other topics appropriate to the category may also be offered. Course may be repeated for credit, provided there is no duplication of specific topic.

CHEM681 Special Topics in Physical Chemistry Course Page

Description: Prerequisite: consent of instructor. Course may be repeated for credit, provided there is no duplication of specific topic.