Quick Course Search

Biochemistry

In order to see more information about any course, simply click on it!

This view does not contain classes that have not been offered in the past 2 years. If you want to view those classes click here:
All Courses

BIOCH200 Introductory Biochemistry Course Page

Description: An introduction to the fundamental principles of biochemistry. Protein structure and function; enzymes; lipids and the structure of biological membranes; nucleotides and the structure of nucleic acids; bioenergetics and the catabolism of carbohydrates. Prerequisites: CHEM 101 and CHEM 261 or 164, or SCI 100.

BIOCH299 Research Opportunity Program Course Page

Description: A credit/no-credit course under the supervision of an academic member of the Department of Biochemistry. Normally taken after completion of a minimum of *30 but not more than *60 in a program in the Faculty of Science. Prerequisite: GPA of 2.7 or higher, BIOCH 200, and consent of department. Normally taken in addition to a full course load. Note: Application does not guarantee a position. Credit may be obtained twice.

BIOCH310 Bioenergetics and Metabolism Course Page

Description: This course is designed to enable rigorous study of the molecular mechanisms in bioenergetics and metabolism. It covers: the principles of bioenergetics; the reactions and pathways of carbohydrate, lipid, and nitrogen metabolism, and their regulation; oxidative phosphorylation; the integration and hormonal regulation of mammalian metabolism. Prerequisites: BIOCH 200, CHEM 102 (or SCI 100) and CHEM 263 with a minimum GPA of 2.70 for these three courses. In the case of over-subscription, preference will be given to students enrolled in programs with a requirement for this course.

BIOCH320 Structure and Catalysis Course Page

Description: This course is designed to illustrate, in detail, the relationships between structure and function in biological molecules. It covers: the structure of proteins; experimental techniques used to study proteins; selected illustrations of protein function; enzyme catalysis, kinetics, and regulation; structural carbohydrates and glycobiology; the structure of lipids; biological membranes and mechanisms of transport. Prerequisites: BIOCH 200, CHEM 102 (or SCI 100) and CHEM 263 with a minimum GPA of 2.70 for these three courses. In the case of over-subscription, preference will be given to students enrolled in programs with a requirement for this course.

BIOCH330 Nucleic Acids and Molecular Biology Course Page

Description: This course is designed to provide students with a comprehensive introduction to the biochemistry of nucleic acids. It covers: the structure and properties of nucleotides and nucleic acids; DNA-based information technologies; genes and chromosome structure; molecular mechanisms in DNA replication, repair, and recombination; RNA metabolism; protein synthesis and targeting; the regulation of gene expression. Prerequisites: BIOCH 200, CHEM 102 (or SCI 100), and CHEM 263, with a minimum GPA of 2.70 for these three courses. In the case of over-subscription, preference will be given to students enrolled in programs with a requirement for this course.

BIOCH398 Research Project Course Page

Description: Supervised research within a laboratory in the Department of Biochemistry. The results of the research project will be presented in a poster. This course is available only as a six week Spring or Summer session course. Prerequisites: Credit in at least one 300-level BIOCH course and consent of the Department. BIOCH 398 may not be taken for credit if credit has been obtained in BIOCH 498 or 499.

BIOCH401A Biochemistry Laboratory Course Page

Description: Laboratory course in modern biochemical techniques. Designed for Biochemistry Honors and Specialization students in their third or fourth year. Other interested students may enrol subject to space limitations. Prerequisites: BIOCH 320 and 330 with a minimum grade of B-, and consent of Department.

BIOCH401B Biochemistry Laboratory Course Page

Description: Laboratory course in modern biochemical techniques. Designed for Biochemistry Honors and Specialization students in their third or fourth year. Other interested students may enrol subject to space limitations. Prerequisites: BIOCH 320 and 330 with a minimum grade of B-, and consent of Department.

BIOCH410 Signal Transduction Course Page

Description: Principles of the biochemistry of cell communication and signal transduction through receptor activation, the generation of second messengers, and the control of protein modifications. The course will emphasize the mechanisms responsible for the regulation of cell migration, division and death. Prerequisites: BIOCH 310, 320 and 330, all with a minimum grade of B-, or consent of the Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 510).

BIOCH420 Proteins: Structure, Function, and Regulation Course Page

Description: Principles of protein structure, function, and dynamics, with an introduction to force fields used in modern molecular dynamics. Focus topics include an introduction to intrinsically disordered proteins and their role in misfolding diseases, the structural biology, ligand binding, and mechanisms of membrane bound enzymes, and mechanisms underlying the regulation of protein function and enzymes involved in cell signaling. Prerequisites: BIOCH 320, with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 520).

BIOCH425 Proteomics Course Page

Description: An advanced course focusing on the analysis of protein function and protein-protein interactions within the context of the entire protein complement of a cell. Some aspects of protein structure as it pertains to the principles of protein-protein interactions will be covered along with genetic and biochemical methods for the analysis of protein complexes, protein interaction networks and system wide protein identification and dynamics. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Prerequisites: BIOCH 320 and BIOCH 330 with a minimum GPA of 3.0 in these courses.

BIOCH430 Biochemistry of Eukaryotic Gene Expression Course Page

Description: The organization and expression at the molecular level of information encoded in the nucleic acids of eukaryotic cells. The focus will be on genome structure and the regulation of gene expression at the levels of transcription, post-transcriptional processing, translation, post-translational modification and protein sorting. Recombinant DNA technologies and genetic engineering will be discussed as methods for studying the cellular processing of genetic information. Prerequisites: BIOCH 320 and 330, both with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 530).

BIOCH441 Structure and Function of Biological Membranes Course Page

Description: Survey of the structure and function of biological membranes. Topics include the structure, properties and composition of biomembranes, characterization and structural principles of membrane lipids and proteins, lateral and transverse asymmetry, dynamics, lipid-protein interactions, membrane enzymology, permeability, and biogenesis. Prerequisites: BIOCH 320, with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 541).

BIOCH450 The Molecular Biology of Mammalian Viruses Course Page

Description: This course will focus on virus structure, replication, and interaction with host cells at the molecular level. Lytic viruses with single- or double-stranded DNA or RNA genomes will be discussed, as will the mechanisms of viral oncogenesis. Prerequisites: BIOCH 320 and 330, with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 550).

BIOCH455 Biochemistry of Lipids and Lipoproteins Course Page

Description: Advanced course focusing on specific aspects of the regulation of lipid and lipoprotein metabolism. Topics include the transcriptional and post-translational mechanisms governing the synthesis and degradation of important enzymes, lipids, and lipid transport molecules; the role of lipid mediators in signaling pathways and protein modification; the assembly and dynamics of lipoproteins and biological membranes; genetic disruptions of lipid regulatory proteins such as cell surface receptors leading to human disease. Prerequisites: BIOCH 310 with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 555).

BIOCH465 Methods in Molecular Biophysics Course Page

Description: Survey of biophysical methods used in the characterization and structural determination of biological macromolecules, from ensemble measurements to single-molecule detection. Topics include mass spectrometry, optical spectroscopy, light microscopy, X-ray and neutron diffraction, electron microscopy, molecular dynamics and nuclear magnetic resonance. Emphasis is on using techniques in evaluating structure-function relationships through the discussion of representative macromolecular systems. Prerequisites: BIOCH 320 with a minimum grade of B- or consent of the Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. This course cannot be taken for credit if credit has already been obtained in BIOCH 460.

BIOCH481 Design and Construction of Synthetic Biological Systems I Course Page

Description: This course explores both the opportunities and challenges of synthetic life by providing a practical and theoretical introduction to this new discipline through lectures, class discussion, assigned reading and case studies. Topics covered include: natural vs artificial design of genetic circuits and devices, experimental aspects of gene and gene network construction, metabolic network design and evaluation, and the role of computer modeling in design creation, testing and optimization. The availability of BIOCH 481 to students from non-biochemistry backgrounds emphasizes the highly interdisciplinary nature of the field. Prerequisites: Registration in the Faculties of Science or Engineering and a minimum GPA 3.3 (or consent of the department).

BIOCH482 Design and Construction of Synthetic Biological Systems II Course Page

Description: Designed to prepare students for participation in the iGEM Competition (International Genetically Engineered Machines) through team-based problem solving. Teams composed of individuals from different programs are expected to: 1) Identify a relevant problem within the realm of synthetic biology. 2) Devise a credible and detailed plan to solve an aspect of the problem. 3) Demonstrate the feasibility of the design by computer modeling. 4) Evaluate the costs of success in terms of the financial, human and technological resources that are needed for the timely completion of the project. 5) Develop a plan to acquire the resources that are required for a successful outcome. 6) Produce a report and presentation. Although students are expected to exhibit a high level of independence and creativity, they can count on considerable guidance and support from participating faculty. Prerequisites: BIOCH 481 (or consent of the department).

BIOCH495 Special Topics in Biochemistry Course Page

Description: Covers specialized topics of current interest to advanced undergraduates in Biochemistry programs. Consult the Department for details about current offerings. Prerequisites: BIOCH 310, 320 and 330, and consent of the instructor. This course is restricted to students in Honors or Specialization in Biochemistry. Credit for this course may be obtained more than once.

BIOCH497 International Directed Research Project Course Page

Description: Supervised research within an international laboratory assigned by the Department of Biochemistry, to be carried out over one term (Spring or Summer). The results of the research project will be presented in an oral presentation. Can be taken as a science elective but not as a substitute for required courses in biochemistry. Can be taken for credit in addition to BIOCH 498 and BIOCH 499. Prerequisites: BIOCH 401 and consent of the Department.

BIOCH498 Directed Research Project Course Page

Description: Supervised research within a laboratory in the Department of Biochemistry, to be carried out over one term (Fall or Winter). The results of the research project will be presented in a short seminar. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. This course is not a substitute for required courses in Biochemistry. Can be taken for credit prior to BIOCH 499.

BIOCH499A Directed Research Project Course Page

Description: Supervised research within a laboratory in the Department of Biochemistry, to be carried out over both terms of Fall/Winter. The results of the research project will be presented in a final written report and an oral presentation. This course is required for the Honors program, but can be taken as a science elective by students in the Specialization program. Students in other programs may be admitted subject to availability. Prerequisites: BIOCH 401 and consent of the Department.

BIOCH499B Directed Research Project Course Page

Description: Supervised research within a laboratory in the Department of Biochemistry, to be carried out over both terms of Fall/Winter. The results of the research project will be presented in a final written report and an oral presentation. This course is required for the Honors program, but can be taken as a science elective by students in the Specialization program. Students in other programs may be admitted subject to availability. Prerequisites: BIOCH 401 and consent of the Department.

BIOCH510 Signal Transduction Course Page

Description: Principles of the biochemistry of cell communication and signal transduction through receptor activation, the generation of second messengers, and the control of protein modifications. The course will emphasize the mechanisms responsible for the regulation of cell migration, division and death. Prerequisites: BIOCH 310, 320 and 330, or BIOCH 203 and 205, all with a minimum grade of B-, or consent of the Department. Lectures are the same as for BIOCH 410, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 410.

BIOCH520 Protein Chemistry, Structure, and Function Course Page

Description: Protein chemistry and purification. The intra- and intermolecular forces that determine protein structure. Principles of protein folding and dynamics. Enzyme mechanisms and ligand binding interactions. Prerequisites: BIOCH 320, or BIOCH 203 and 205, all with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 420, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 420.

BIOCH525 Proteomics Course Page

Description: An advanced course focusing on the analysis of protein function and protein-protein interactions within the context of the entire protein complement of a cell. Some aspects of protein structure as it pertains to the principles of protein-protein interactions will be covered along with genetic and biochemical methods for the analysis of protein complexes, protein interaction networks and system wide protein identification and dynamics. This course is intended for students in Biochemistry but students in other programs may be admitted subject to availability and with the consent of the Department. Prerequisites: BIOCH 420 and BIOCH 430 or their equivalent with a minimum GPA of 3.2 in these courses.

BIOCH530 Biochemistry of Eukaryotic Gene Expression Course Page

Description: The organization and expression at the molecular level of information encoded in the nucleic acids of eukaryotic cells. The focus will be on genome structure and the regulation of gene expression at the levels of transcription, post-transcriptional processing, translation, post-translational modification and protein sorting. Recombinant DNA technologies and genetic engineering will be discussed as methods for studying the cellular processing of genetic information. Prerequisites: BIOCH 320 and 330, or BIOCH 203 and 205, all with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 430, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 430.

BIOCH541 Structure and Function of Biological Membranes Course Page

Description: Survey of the structure and function of biological membranes. Topics include the structure, properties and composition of biomembranes, characterization and structural principles of membrane lipids and proteins, lateral and transverse asymmetry, dynamics, lipid-protein interactions, membrane enzymology, permeability, and biogenesis. Prerequisites: BIOCH 320, or BIOCH 203 and 205, all with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 441, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 441.

BIOCH550 The Molecular Biology of Mammalian Viruses Course Page

Description: This course will focus on virus structure, replication, and interaction with host cells at the molecular level. Lytic viruses with single- or double-stranded DNA or RNA genomes will be discussed, as will the mechanisms of viral oncogenesis. Prerequisites: BIOCH 320 and 330, or BIOCH 203 and 205, all with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 450, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 450.

BIOCH555 Biochemistry of Lipids and Lipoproteins Course Page

Description: Advanced course focusing on specific aspects of the regulation of lipid and lipoprotein metabolism. Topics include the transcriptional and post-translational mechanisms governing the synthesis and degradation of important enzymes, lipids, and lipid transport molecules; the role of lipid mediators in signaling pathways and protein modification; the assembly and dynamics of lipoproteins and biological membranes; genetic disruptions of lipid regulatory proteins such as cell surface receptors leading to human disease. Prerequisites: BIOCH 310 with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 455, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 455.

BIOCH565 Methods in Molecular Biophysics Course Page

Description: Survey of biophysical methods used in the characterization and structural determination of biological macromolecules, from ensemble measurements to single-molecule detection. Topics include mass spectrometry, optical spectroscopy, light microscopy, X-ray and neutron diffraction, electron microscopy, molecular dynamics and nuclear magnetic resonance. Emphasis is on using techniques in evaluating structure-function relationships through the discussion of representative macromolecular systems. Lectures are the same as for BIOCH 465, but with additional assignments and evaluation appropriate to graduate studies. This course cannot be taken for credit if credit has already been obtained in BIOCH 460 or 465.

BIOCH609 Macromolecular Structure Analysis Course Page

Description: Principles of X-ray crystallography as applied to the study of protein and nucleic acid structure. Practical aspects of diffraction and structure solution are demonstrated by a collaborative study of a suitable small molecule of biological interest. Designed for senior honors and graduate students. Prerequisite: consent of Instructor. Maximum enrolment of 10 students. Offered in alternate years.

BIOCH620 Selected Topics in Protein Structure, Function, and Regulation Course Page

Description: Directed reading and seminar course, based on papers taken from recent literature of protein research. Students critically discuss the papers and give oral presentations to the class. Designed for graduate students. Prerequisite: BIOCH 420 or equivalent, or consent of Department.

BIOCH623A Special Topics in Research on Polynucleotides Course Page

Description: This course is a journal club and discussion group in which current research topics on nucleic acids are discussed. Specific talks range from biochemistry, genetics and microbiology to nuclear biology and clinical aspects.

BIOCH623B Special Topics in Research on Polynucleotides Course Page

Description: This course is a journal club and discussion group in which current research topics on nucleic acids are discussed. Specific talks range from biochemistry, genetics and microbiology to nuclear biology and clinical aspects.

BIOCH626A Special Topics in Protein Research Course Page

Description: Seminar course for advanced students. Detailed consideration is given to recent advances in research on protein structure and function and mechanism of enzyme action. Prerequisite: BIOCH 420 or consent of Department.

BIOCH626B Special Topics in Protein Research Course Page

Description: Seminar course for advanced students. Detailed consideration is given to recent advances in research on protein structure and function and mechanism of enzyme action. Prerequisite: BIOCH 420 or consent of Department.

BIOCH630 Selected Topics in Modern Molecular Biology Course Page

Description: Directed reading and seminar course, based on papers taken from the recent literature of molecular biology. Students critically discuss the papers and give oral presentations. Note: designed for graduate students; offered yearly. Prerequisite: BIOCH 530 and consent of the Department.

BIOCH640A Special Topics in Research on Biomembranes Course Page

Description: Seminar course for advanced students covering selected topics from the current literature in the field of membrane structure and function. Prerequisite: BIOCH 441 or consent of Department.

BIOCH640B Special Topics in Research on Biomembranes Course Page

Description: Seminar course for advanced students covering selected topics from the current literature in the field of membrane structure and function. Prerequisite: BIOCH 441 or consent of Department.

BIOCH641 Selected Topics on the Structure and Function of Biological Membranes Course Page

Description: Directed reading and seminar course on the structure and function of biological membranes. Topics include membrane biogenesis, bioenergetics, transport and structural aspects of membrane lipids and proteins. Prerequisite: BIOCH 441 or consent of the Department.

BIOCH650A Signal Transduction Course Page

Description: A journal club and discussion group addressing topics in the general area of signalling mechanisms that control cell activation, growth, apoptosis and vesicle trafficking. Specific talks range from biochemistry, genetics and microbiology to molecular biology and clinical aspects. Prerequisite: BIOCH 410/510 or consent of Department.

BIOCH650B Signal Transduction Course Page

Description: A journal club and discussion group addressing topics in the general area of signalling mechanisms that control cell activation, growth, apoptosis and vesicle trafficking. Specific talks range from biochemistry, genetics and microbiology to molecular biology and clinical aspects. Prerequisite: BIOCH 410/510 or consent of Department.

BIOCH651A Special Topics in Lipid and Lipoprotein Research Course Page

Description: Seminar for advanced students covering selected topics from the current literature in the field of lipid and lipoprotein research. Prerequisite: BIOCH 555 or consent of Department.

BIOCH651B Special Topics in Lipid and Lipoprotein Research Course Page

Description: Seminar for advanced students covering selected topics from the current literature in the field of lipid and lipoprotein research. Prerequisite: BIOCH 555 or consent of Department.

BIOCH655 Advances in Lipid and Lipoprotein Research Course Page

Description: Recent developments and use of the current literature are emphasized. Topics include regulation of lipid metabolism, intracellular lipid trafficking, regulation of lipoprotein secretion, lipid transfer among lipoproteins, reverse cholesterol transport, and atherosclerosis. Prerequisite: BIOCH 455, or 555, or consent of Department. Offered in alternate years.

BIOCH670A Recent Advances in Biochemistry Course Page

Description: A seminar course on topics of current interest in biochemistry. Students will contribute to a presentation based on recent developments published in first rate journals. Attendance at all seminars is expected. Note: open only to graduate students in Biochemistry.

BIOCH670B Recent Advances in Biochemistry Course Page

Description: A seminar course on topics of current interest in biochemistry. Students will contribute to a presentation based on recent developments published in first rate journals. Attendance at all seminars is expected. Note: open only to graduate students in Biochemistry.

BIOCH671A Recent Advances in Biochemistry Course Page

Description: A seminar course on topics of current interest in biochemistry. Students will contribute a presentation on their research project that includes original data. Attendance at all seminars is expected. Prerequisite: BIOCH 670 or consent of the Department. Note: open only to graduate students in Biochemistry.

BIOCH671B Recent Advances in Biochemistry Course Page

Description: A seminar course on topics of current interest in biochemistry. Students will contribute a presentation on their research project that includes original data. Attendance at all seminars is expected. Prerequisite: BIOCH 670 or consent of the Department. Note: open only to graduate students in Biochemistry.

BIOCH675 Magnetic Resonance in Biology and Medicine II Course Page

Description: Designed for advanced honors and graduate students interested in the application of nuclear magnetic resonance spectroscopy to biological systems. Topics include quantum mechanical basis of NMR, multinuclear multidimensional NMR experiments, NMR relaxation theory, new NMR applications. Prerequisite: consent of Instructor. Offered in alternate years.